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Review Case Reports
Cardiac Arrest Following Remimazolam-Induced Anaphylaxis: A Case Report.
- Yudai Hasushita, Megumi Nagao, Yoshihide Miyazawa, Kazuma Yunoki, and Hiroyuki Mima.
- From the Departments of Anesthesiology and Intensive Care.
- A A Pract. 2022 Sep 1; 16 (9): e01616e01616.
AbstractRemimazolam is a recently approved benzodiazepine sedative. We report a case of a 72-year-old man who experienced a cardiac arrest due to severe anaphylaxis immediately after general anesthesia induction. Based on the results of skin tests, including those for dextran 40, an excipient in the remimazolam solution, and a review of drugs given during 3 anesthetics, remimazolam was identified as the probable causative agent. Although remimazolam is structurally similar to midazolam, the patient was not allergic to midazolam as demonstrated before and after anaphylaxis. This report highlights the potential risk of allergic reactions to remimazolam.Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Anesthesia Research Society.
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