• Xing Hu, Yan-Ming Ren, Xiang Yang, Xiao-Dong Liu, Bo-Wen Huang, Teng-Yun Chen, Yan Jv, Zhi-Gang Lan, Wen-Ke Liu, Xue-Song Liu, Xu-Hui Hui, Jing-Ping Liu, and Yue-Kang Zhang.
• Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, PR China.
• World Neurosurg. 2023 Apr 1; 172: e1e11e1-e11.

BackgroundThe pineal tumor was once considered as a restricted area for surgery. Such cases are rare, with many different opinions on surgical treatment. This study aimed to review our experience of tumor treatment in the pineal region and explore the optimal treatment strategy.MethodsThe clinical data of 72 patients with pineal tumors from January 1997 to May 2015 (18 years) were retrospectively analyzed. Preoperative preparation, pathology type, tumor resection rate, surgical approach, and follow-up outcomes were used as the indicators to evaluate the treatment efficacy.ResultsThe Krause approach was used in 46 cases, the Poppen approach in 10 cases, and the transcallosal-lateral ventricle-choroid fissure approach in 16 cases. The postoperative pathological results were as follows: 24 cases of germinoma, 11 of teratoma, 15 of glioma, 6 of meningioma, 11 of Pineocytoma, 2 of cholesteatoma, 2 of cavernous hemangioma, and 1 of choriocarcinoma. Further, the study included 64 cases of total surgical resections, 8 of subtotal resections, and 2 deaths. The follow-up period was from 7 months to 10 years. Further, 51 (70.8%) patients were followed up. The multivariate regression model showed that the surgical method and the pathological type contributed significantly to predicting outcomes.ConclusionsThe type of pathology, extent of excision, and surgical approach had a significant impact on the prognosis of patients. The transcallosal-lateral ventricle-choroid fissure approach for large and medium-sized pineal tumors near the posterior part of the third ventricle had good efficacy.Copyright © 2022. Published by Elsevier Inc.

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