• William E Balch, Jacob I Sznajder, Scott Budinger, Daniel Finley, Aaron D Laposky, Ana Maria Cuervo, Ivor J Benjamin, Esther Barreiro, Richard I Morimoto, Lisa Postow, Allan M Weissman, Dorothy Gail, Susan Banks-Schlegel, Thomas Croxton, and Weiniu Gan.
• 1 Department of Cell Biology and Chemical Physiology, The Scripps Research Institute, La Jolla, California.
• Am. J. Respir. Crit. Care Med.. 2014 Jan 1;189(1):96-103.

AbstractRecent discoveries indicate that disorders of protein folding and degradation play a particularly important role in the development of lung diseases and their associated complications. The overarching purpose of the National Heart, Lung, and Blood Institute workshop on "Malformed Protein Structure and Proteostasis in Lung Diseases" was to identify mechanistic and clinical research opportunities indicated by these recent discoveries in proteostasis science that will advance our molecular understanding of lung pathobiology and facilitate the development of new diagnostic and therapeutic strategies for the prevention and treatment of lung disease. The workshop's discussion focused on identifying gaps in scientific knowledge with respect to proteostasis and lung disease, discussing new research advances and opportunities in protein folding science, and highlighting novel technologies with potential therapeutic applications for diagnosis and treatment.

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