• Robert L Chatburn and Ping-Hui Liu.
• Enterprise Respiratory Care Research, Cleveland Clinic, Cleveland, Ohio; and Department of Medicine, Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio. chatbur@CCF.org.
• Respir Care. 2023 Mar 1; 68 (3): 417428417-428.

AbstractIntermittent mandatory ventilation (IMV) is one kind of breath sequence used to classify a mode of ventilation. IMV is defined as the ability for spontaneous breaths (patient triggered and patient cycled) to exist between mandatory breaths (machine triggered or machine cycled). Over the course of more than a century, IMV has evolved into 4 distinct varieties, each with its own advantages and disadvantages in serving the goals of mechanical ventilation (ie, safety, comfort, and liberation). The purpose of this paper is to describe the evolution of IMV, review relevant supporting evidence, and discuss the rationales for each of the 4 varieties. Also included is a brief overview of the background information required for a proper perspective of the purpose and design of the innovations. Understanding these different forms of IMV is essential to recognizing the similarities and differences among many dozens of different modes of ventilation. This recognition is important for clinical application, education of caregivers, and research in mechanical ventilation.Copyright © 2023 by Daedalus Enterprises.

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