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- Dayane Caroliny Pereira Justino, David Franciole Oliveira Silva, Ketyllem Tayanne da Silva Costa, Thiffany Nayara Bento de Morais, and Fábia Barbosa de Andrade.
- Department of Public Health, Federal University of Rio Grande do Norte, Brazil.
- Medicine (Baltimore). 2022 Sep 23; 101 (38): e30246e30246.
BackgroundIn December 2019, a new disease, coronavirus disease (COVID-19), emerged, which put several countries on a state of alert. Because it is a novel virus, several aspects and factors that contribute to the evolution of pathogenesis are still unknown and need to be better understood. Therefore, a systematic review is necessary to investigate the association between COVID-19 infection and chronic nontransmissible disease in patients who have died of COVID-19.MethodsThis was a systematic review of the literature for observational studies published between December 2019 and September 2020. The protocol for this systematic review was registered in the International prospective register of systematic reviews (PROSPERO) under the number CRD42020176249.ResultsIn the 31 studies analyzed, a total of 421,872 (100%) patients were infected with COVID-19, and, of these, 45,399 (10.8%) died. The 3 most prevalent comorbidities were hypertension, diabetes mellitus, and respiratory diseases, respectively. The cure/recovery rate was 89.2% (376,473).ConclusionThis review revealed a high percentage of comorbidities in the patients with COVID-19, especially those who died.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
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