• Medicine · Sep 2022

    Review

    Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA).

    • Yifei Zhang, Asal Aa Mostafa, Natthida Sriboonvorakul, and Jiamiao Hu.
    • Engineering Research Centre of Fujian-Taiwan Special Marine Food Processing and Nutrition, Ministry of Education, Fuzhou, Fujian, China.
    • Medicine (Baltimore). 2022 Sep 23; 101 (38): e30587.

    AbstractActivator protein-2 gamma (AP-2γ) is a crucial transcription factor involved in breast cancer development. Abnormal expression and activity of AP-2γ have also been identified as important markers of malignancy. In the last decade, the importance of AP-2γ in breast cancer progression has been widely studied. In this review, we summarize the current knowledge on the regulatory roles of AP-2γ in breast cancer oncogenesis and progression and its potential as a diagnostic biomarker and drug target in breast cancer treatment.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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