• Lixia Niu, Sufang Wang, Yunyun Li, and Jun Liu.
• Department of Ophthalmology, Changzhi People's Hospital, Changzhi, China.
• Medicine (Baltimore). 2022 Oct 7; 101 (40): e30956e30956.

IntroductionPreviously, diagnosis of ocular toxoplasmosis is based on clinical symptoms and Toxoplasma serology. Checking serological indicators often cannot reflect the real intraocular situation, and may even mislead clinicians to make wrong judgments.Patient ConcernsA 38-year-old male patient visited our ophthalmology clinic with a chief complaint of decreased vision for about 5 days in his right eye.DiagnosisAqueous humor sample analysis found Toxoplasma DNA detectable, and Toxoplasma immunoglobulin G (IgG) and immunoglobulin M (IgM) to be positive. His serum Toxoplasma IgG was also positive (10.04 IU/mL; reference range: 0 to 7.2 IU/mL). Therefore, the final diagnose was ocular toxoplasmosis involving his right eye.InterventionsOral prednisone 60 mg/day and azithromycin 0.25 g/day were started. Oral antibiotic treatment for toxoplasma was continued for 4 weeks, and prednisone followed by weekly stepwise tapering in steps of 10 mg/day.OutcomesThe BCVA and fundus of right eye remained stable after treatment at follow-up.ConclusionsThis article reported a case of ocular Toxoplasma gondii infection diagnosis by serum and aqueous humor antibody tests. We provide some additional information on the T gondii infection diagnosis.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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