• Kai Zhao, Jiang Zhou, Jing Tao Guo, Cai Hong Wu, Sen Lin Li, Qi Zhang, Xiang Tian, Wei Chao Shan, Zhen Jiang Ding, Lan Suo Yuan, Qun Zheng, Xiao Li Gao, Nan Guo, Hong Sen Tian, Qing Min Wei, Xi Tian Hu, Ying Kai Cui, Xue Geng, Qian Wang, and Wei Cui.
• Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
• Ann. Med. 2022 Dec 1; 54 (1): 289829082898-2908.

BackgroundThere is scant data on the association of the Pulsed wave-Doppler tissue imaging (PW-DTI)-derived tricuspid lateral annular peak systolic velocity (S') and poor short-term prognosis of patients with acute decompensated heart failure (ADHF).Patients And MethodsA total number of 732 participants from the Heb-ADHF registry in China were divided into three groups according to the corresponding status of tricuspid S'. Demographic characteristics, comorbidities, physical examinations, lab tests, and medications were compared among the different groups. Different logistic regression models were utilized to gauge the relationship between S' and the risk of a composite of short-term all-cause mortality or 30-day heart failure (HF)-related rehospitalization.ResultsThe number of composite outcome events identified in the study population was 85, with the short-term all-cause death coupled with 30-day HF readmission events reaching 23 and 62, respectively. As per the multivariable adjusted analysis, S' was inversely related to the risk of a composite outcome [<10 cm/s odds ratios (OR) 2.90, 95% confidence interval (CI):1.33-6.31; 10-11 cm/s OR 2.18, 95% CI: 1.10-4.33; p for trend = 0.006] in comparison with S' at >11 cm/s. When S' was analysed as a continuous variable, per 1 cm/s increase, the OR (95% CI) for a composite outcome was [0.87 (0.77-0.99), p = 0.028]. Area under curve (AUC) of S' for predicting outcome of ADHF was 0.631 (95%CI: 0.573-0.690, p < 0.01). Significant inverse association was also observed in left ventricular ejection fraction (LVEF) ≥40% subgroup.ConclusionsInspite of the potential confounders, a more impaired tricuspid annular peak systolic velocity is associated with a poorer short-term prognosis of patients with ADHF.

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