• Guillaume L Martin, Alice Atramont, Marjorie Mazars, Ayden Tajahmady, Emin Agamaliyev, Mervyn Singer, Marc Leone, and Matthieu Legrand.
• Caisse Nationale de l'Assurance Maladie, Paris, France.
• Chest. 2023 Apr 1; 163 (4): 826842826-842.

BackgroundBeyond the question of short-term survival, days spent at home could be considered a patient-centered outcome in critical care trials.Research QuestionWhat are the days spent at home and health care trajectories during the year after surviving critical illness?Study Design And MethodsData were extracted on adult survivors spending at least 2 nights in a French ICU during 2018 who were treated with invasive mechanical ventilation or vasopressors or inotropes. Trauma, burn, organ transplant, stroke, and neurosurgical patients were excluded. Stays at home, death, and hospitalizations were reported before and after ICU stay, using state sequence analysis. An unsupervised clustering method was performed to identify cohorts based on post-ICU trajectories.ResultsOf 77,132 ICU survivors, 89% returned home. In the year after discharge, these patients spent a median of 330 (interquartile range [IQR], 283-349) days at home. At 1 year, 77% of patients were still at home and 17% had died. Fifty-one percent had been re-hospitalized, and 10% required a further ICU admission. Forty-eight percent used rehabilitation facilities, and 5.7%, hospital at home. Three clusters of patients with distinct post-ICU trajectories were identified. Patients in cluster 1 (68% of total) survived and spent most of the year at home (338 [323-354] days). Patients in cluster 2 (18%) had more complex trajectories, but most could return home (91%), spending 242 (174-277) days at home. Patients in cluster 3 (14%) died, with only 37% returning home for 45 (15-90) days.InterpretationMany patients had complex health care trajectories after surviving critical illness. Wide variations in the ability to return home after ICU discharge were observed between clusters, which represents an important patient-centered outcome.Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

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