• Yuji Yoshikawa, Junji Kanno, Kei Shinoda, and Jun Makita.
• Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan.
• Medicine (Baltimore). 2022 Oct 14; 101 (41): e31018.

AbstractWe evaluated the macular visibility of a newly designed extended depth of focus (EDOF) intraocular lenses (IOL) using a wide viewing system for macular manipulation (Risight;60D, Carl Zeiss Meditec AG) in a model eye and compared it with various other types of IOLs. We used a model eye that was constructed based on the Glustrand model to compare a newly designed EDOF IOL (DIB00V; Johnson & Johnson Surgical Vision), an EDOF IOL with a diffraction grating (ZXR00V; Johnson & Johnson surgical Vision), and a monofocal aspheric (DCB00V; Johnson & Johnson Vision, XY-1; HOYA Surgical Optics, Tokyo, Japan) or spherical IOL (NX70s; Santen Pharmaceutical Co., Ltd). In the model eye, a 1951 United States Air Force (USAF) test was placed at the location of the macula. The contrasts in a range of spatial frequencies were quantified using the images obtained from the 1951 USAF test target. The contrast at each spatial frequency was plotted and integrated to calculate the area under the curve contrast (AUC-contrast). Qualitative evaluations showed that good-quality images were obtained for all IOLs. At a spatial frequency of 16 LP/mm, the average contrast was the highest for the DIB00V and NX70s (0.216 each). The highest average contrast at 32 LP/mm was obtained using the NX70s (0.128), and at 64 LP/mm using the DIB00V (0.123). The horizontal AUC-contrast was the highest for the NX70s (8.754), and the vertical AUC-contrast was the highest for the DIB00V (8.334). On average, the DIB00V had the highest AUC-contrast value (8.227). The high-order aspheric IOL, DIB00V, was found to exhibit good macular visibility despite being an EDOF IOL.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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