• Gengjun Liu, Ying Li, Yaxin Li, Licun Wang, Ping Li, Zheng Liu, Jiao Liu, Dongmei Ge, Gang Zhao, and Haiyan Wang.
• Department of Blood Transfusion, the Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong, China.
• Medicine (Baltimore). 2022 Oct 14; 101 (41): e30016.

RationaleRectum ulcer is a disease of the digestive system, the main symptoms of which includes bloody diarrhea, abdominal pain, hematochezia, etc. At present, drug therapy and surgery are the most common treatments. Platelet-rich plasma (PRP) contains high concentrations of platelets and has been used to promote wound healing. However, the utilization of PRP in rectal ulcers has rarely been reported.Patient ConcernsThe patient had reported a complaint of blood dripping from the stool for more than 4 months. She had a history of surgery for rectal cancer with postoperative chemotherapy and radiotherapy 19 years prior. Mesalazine suppository was given to her for about 4 months, and glutamine capsules for 2 months, but the rectal ulcer remained unhealed.DiagnosisA rectal ulcer was observed on colonoscopy, and the biopsy result was tubular adenoma.InterventionsAutologous PRP treatment was performed for the patient under an anorectal scope together with basic supportive care.OutcomesThe ulcer nearly healed within 9 days after twice PRP treatments.LessonsPRP treatment may bring about novel treatment options for rectal ulcers.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

14 keywords...

hide…