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Case Reports
A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma.
- Kentaro Sato, Hidemichi Imamura, Yu Watahiki, Hiromasa Hazama, Takeaki Hashimoto, Shinji Mukae, and Hiromasa Ohhira.
- Department of Gastroenterology, Aizu Medical Center, Japan.
- Intern. Med. 2023 Jun 1; 62 (11): 161116151611-1615.
AbstractAn 81-year-old man underwent rituximab-containing chemotherapy for chronic lymphocytic leukemia (CLL). Thirteen years after his last chemotherapy, he was diagnosed with hepatitis B virus (HBV) reactivation. He was then treated with entecavir, and improvement was seen in his liver injury. He developed diffuse large B cell lymphoma (DLBCL) after improvement in his hepatitis. Despite chemotherapy, he contracted the coronavirus disease 2019 (COVID-19) and died of COVID-19. We suspect that HBV reactivation was triggered by DLBCL. When HBV reactivation occurs a long time after chemotherapy has concluded, the onset of DLBCL should be considered.
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