• Ikumi Takagi, Hiroaki Akiyama, Hiroyuki Matsuba, Junpei Rikitake, Yoko Kozuki, Yoshiharu Miyata, Mai Nakanishi, Mayumi Inaba, Nobuko Iwata, and Seiji Kakiuchi.
• Department of Hematology, Yodogawa Christian Hospital, Japan.
• Intern. Med. 2023 Jun 15; 62 (12): 186118661861-1866.

AbstractCytomegalovirus (CMV) oophoritis is an extremely rare and fatal condition. We encountered a 63-year-old woman with CMV oophoritis who had been treated for Burkitt's lymphoma. Positron emission tomography/computed tomography performed after chemotherapy showed a high 18F-fluoro-2deoxy-D-glucose uptake in both ovaries, which required distinguishing relapse. CMV oophoritis was diagnosed on histology following bilateral salpingo-oophorectomy. Although the patient later developed recurrent episodes of CMV antigenemia, after which complications of CMV retinitis appeared, and she ultimately died of CMV meningitis, surgical resection with antiviral medication resolved her abdominal symptoms and cleared CMV antigenemia for several weeks. It is therefore worth considering surgical resection in combination with antiviral drugs as a treatment option.

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