• G E Baimakanova, I E Khatkov, G A Dudina, A S Chegodar, K A Rumyantsev, F S Sviridov, A V Osipova, A M Danishevich, K K Noskova, E S Pinashina, N V Orlova, V M Slezinger, M E Chernova, K A Tovstyko, and N A Bodunova.
• Loginov Moscow Clinical Scientific and Practical Center.
• Terapevt Arkh. 2021 Nov 15; 93 (11): 1283-1289.

AimEvaluation of the clinical characteristics in patients with COVID-19.Materials And MethodsThe article presents clinical and instrumental data of 1169 patients included in a single-center mixed study. Patients were tested for COVID-19 using polymerase chain reaction, computed tomography (CT), and antibody screening. Clinical history data were collected.ResultsIn patients with confirmed COVID-19, lung damage and a positive test for antibodies were observed in 75.5 and 45.2% of cases, respectively. The most common symptoms of COVID-19 were: fever (73.2%), weakness, (72.7%) dry cough (62.8%) and shortness of breath (55.4%). Patients with CT-visualized lung lesions were more likely to have clinical symptoms and elevated levels of antibodies. Patients with chronic diseases of the endocrine system, circulatory system, and respiratory system had a more severe course of the disease (CT-14: 91.296.3%) than patients without chronic diseases (CT-14: 85,1%).ConclusionWe have compiled a clinical profile of patients with COVID-19 and highlighted the most significant clinical characteristics corresponding to a more severe course of the disease. Our data showed that patients with chronic diseases require a personalized approach and the development of specific criteria for the diagnosis and treatment of COVID-19.

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