• Terapevt Arkh · Jun 2021

    [Role of the intestinal MALT in pathogenesis of the IgA-nephropathy].

    • S V Guliaev, L A Strizhakov, N V Chebotareva, and S V Moiseev.
    • Sechenov First Moscow State Medical University (Sechenov University).
    • Terapevt Arkh. 2021 Jun 15; 93 (6): 724-728.

    AbstractModern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed in details. Based on supposed entero-renal pathogenesis of the disease future treatment modalities are considered. Relevant worlds literature is cited.

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