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- Yong Seng Tam, Elizabeth Chen, ZhiSheng Edmund Poh, Gerksin Chia, Mahrley Provido, Allyn Hum, and Hsien Xiong Lee.
- Department of Palliative Medicine, Tan Tock Seng Hospital, Singapore, Singapore.
- J Palliat Med. 2023 Apr 1; 26 (4): 591595591-595.
AbstractCarcinomatosis meningitis is a rare but deadly complication of medulloblastoma. Surgical and systemic treatment options are often limited in advanced stages of the cancer. Meningeal irritation from raised intracranial pressure causes leptomeningeal pain that may respond poorly to opioids and common adjuvant analgesics. We present the case of a terminally ill patient with severe leptomeningeal pain that responded to a trial of ketamine as an adjunct to opioids.
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