• Yuqing Wei, Chengping Wang, Lin Sun, Danyang Wang, and Peng Chen.
• Department of Anesthesiology, China-Japan Union Hospital, Jilin University, Changchun, China.
• Minerva Anestesiol. 2022 Dec 1; 88 (12): 105710651057-1065.

AbstractGoal-directed fluid therapy (GDFT) is currently recognized as a scientific and reasonable method of perioperative capacity management. However, most of the studies on GDFT are carried out in the supine position, while there are few studies on applying GDFT in the prone position. This article introduces the target parameters of GDFT, the influence of prone position on target parameters, and the clinical application of GDFT in the prone position. Many studies have shown that the cut-off values of target parameters such as stroke volume variation (SVV) and pulse pressure variation (PPV) change in the prone position, but the ability to predict fluid responsiveness remains unchanged, which are still helpful indicators for guiding fluid therapy in the prone position. Although it is controversial whether the GDFT strategy can improve the clinical outcome of patients undergoing prone position surgery, it is still the mainstream choice of fluid therapy. In the future, we need to explore further the method of predicting the fluid responsiveness of patients in the prone position, improve the GDFT strategy, and guide the perioperative fluid therapy of patients in the prone position.

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