• Tomasz A Dziedzic, Aleksandra Bala, Jolanta Piwowarska, Anna Podgórska, Agnieszka Olejnik, Kacper Koczyk, and Andrzej Marchel.
• Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland. Electronic address: t.dziedzic@wum.edu.pl.
• World Neurosurg. 2023 Feb 1; 170: e151e158e151-e158.

ObjectiveThere is ongoing discussion on pros and cons in terms of different anesthesia protocols for awake craniotomy (AC) with direct brain stimulation. The aim of this study is to share our anesthesia protocol and present our patients' perspectives.MethodsWe conducted an analysis of prospectively collected data from 53 (54 procedures) consecutive patients. Most of the patients (50) underwent surgery due to primary brain lesions. Eight procedures were performed in patients with lesions in the nondominant hemisphere for language. Four of all procedures were reoperations, and one patient was operated on in awake conditions twice. The psychological evaluation of patients was performed 2 times: 2 days before and after surgery. A visual analog scale for pain and stress levels as well as structured interviews was used.ResultsMost patients tolerated ACwell. Patients reported that discomfort was mostly related to urinary catheter insertion, head holder placement, and temporal muscle detachment in cases of frontotemporal craniotomies. The intensity of stress measured with the visual analog scale before surgery was negatively associated with age and positively correlated with stress experienced in the operating room. In all patients, we were able to finish the procedure according to the monitored anesthesia care protocol without the need for conversion to general anesthesia. We observed 3 (5.6%) intraoperative seizures that required deepening of sedation.ConclusionAC using the monitored anesthesia care protocol was a safe and well-tolerated procedure with satisfactory patient experience. Extensive preoperative preparation should be considered a key part of the procedure.Copyright © 2022. Published by Elsevier Inc.

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