• Claudiu-Eduard Nistor, Adrian Ciuche, Anca Pati Cucu, Cornelia Nitipir, Cristina Slavu, Bogdan Serban, Adrian Cursaru, Bogdan Cretu, and Catalin Cirstoiu.
• Department Thoracic Surgery, Dr. Carol Davila Central Military Emergency University Hospital, 010825 Bucharest, Romania.
• Medicina (Kaunas). 2022 Oct 16; 58 (10).

AbstractLung neoplasm is the main cause of cancer-related mortality, and bone metastasis is among the most common secondary tumors. The vast majority of patients also present with multiple bone metastases, which makes systemic and adjuvant pain therapy preferable to surgery. The optimal approach for a resectable non-small-cell lung tumor that also presents a unique, resectable bone metastasis is not fully established. The number of papers addressing this subject is small, and most are case reports; nevertheless, survival rates seem to increase with radical surgery. The sequencing of local versus systemic treatment should always be discussed within the multidisciplinary team that will choose the best approach for each patient. As targeted systemic therapies become more accessible, radical surgery, together with existing reconstructive methods, will lead to an increase in life expectancy and a better quality of life.

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