• Ugeskrift for laeger · Oct 2011

    Case Reports

    [Icatibant is a new treatment option in life-threatening angioedema triggered by angiotensin-converting enzyme inhibitor].

    • Søren Fast, Emil Henningsen, and Anette Bygum.
    • Øre-næse-hals Afdeling F, Odense Universitetshospital, 5000 Odense C, Denmark. Soeren.Fast@ouh.regionsyddanmark.dk
    • Ugeskr. Laeg. 2011 Oct 10;173(41):2574-5.

    AbstractA 78 year-old woman with life-threatening angiotensin-converting enzyme inhibitor (ACE-i) induced angioedema was unresponsive to conventional treatment with corticosteroids, antihistamines and epinephrine. She was successfully treated with icatibant licensed for treatment of hereditary angioedema knowing that both conditions involve bradykinin induced activation of bradykinin B2 receptors. Randomised, controlled trials are warranted to document the efficacy of icatibant in ACE-i angioedema.

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