• Brit J Hosp Med · Oct 2022

    Review

    Minimising complications and improving the success of peripheral regional blockade.

    • Dominic Wu and Amarjeet Patil.
    • Department of Anaesthesia, Manchester University NHS Foundation Trust, Manchester, UK.
    • Brit J Hosp Med. 2022 Oct 2; 83 (10): 1-10.

    AbstractPeripheral regional blockade is a type of regional anaesthesia involving depositing local anaesthetics around a specific nerve or bundle of nerves that help transmit nociceptive signals to higher centres, such as the thalamus and somatosensory cortex. It is not only a widely used technique that provides surgical anaesthesia, but also acts as an essential part of the armamentarium against postoperative pain and pain following major skeletal trauma. This article discusses the structure and function of peripheral nerves, the classification and pathophysiology of peripheral nerve injury and, finally, how practising anaesthetists are committed to maximising success and minimising harm when performing peripheral nerve blockade in the operating theatre.

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