• Takako Matsuoka, Aoi Miyazaki, Sachiyo Kosai, Kazuyoshi Nakamura, Hideshi Uramoto, Hironori Kobayashi, and Osamu Sakamoto.
• Department of Respiratory Medicine, National Hospital Organization Kumamoto Saishun Medical Center, Japan.
• Intern. Med. 2023 Jun 15; 62 (12): 180118061801-1806.

AbstractA 77-year-old man was referred to our hospital for abnormal thoracic radiographs. Computed tomography (CT) revealed a 20-mm subpleural ground-glass opacity in the right S6 area. A CT-guided biopsy revealed lung adenocarcinoma. Fluorodeoxyglucose-positron emission tomography revealed multiple abnormal bone accumulations, and a subsequent biopsy of a left iliac bone lesion revealed chronic lymphocytic leukemia. A right lower lung lobectomy was performed for the lung adenocarcinoma (cT1bN0M0, stage IA2). An aggressive biopsy of the bone lesion confirmed a rare case of double primary malignancies, which determined the patient's treatment and outcomes.

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