• Med. Clin. North Am. · Jan 2023

    Review

    Frailty: A Multidimensional Biopsychosocial Syndrome.

    • Carl I Cohen, Rivka Benyaminov, Manumar Rahman, Dilys Ngu, and Michael Reinhardt.
    • SUNY Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. Electronic address: carl.cohen@downstate.edu.
    • Med. Clin. North Am. 2023 Jan 1; 107 (1): 183197183-197.

    AbstractThe original conceptual landscape of frailty has evolved into a complex, multidimensional biopsychosocial syndrome. This has broadened the field to now include social and behavioral scientists and clinicians from a wide range of specialties. This article aims to provide an updated overview of this conceptual change by examining the emerging definitions of physical, cognitive, social, and psychological frailty; the tools used for diagnosis and assessment of these domains; the epidemiology of the domains; their pathogenesis, risk factors, and course; frameworks for prevention and treatment; and unresolved issues affecting the field.Copyright © 2022 Elsevier Inc. All rights reserved.

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