• Conf Proc IEEE Eng Med Biol Soc · Jan 2010

    Merging PK/PD information in a minimally parameterized model of the neuromuscular blockade.

    • Margarida Martins da Silva, Juliana Almeida, Torbjorn Wigren, and Teresa Mendonca.
    • Faculdade de Ciências, Univ. Porto, Rua do Campo Alegre, 4169-007, Portugal. margarida.silva@fc.up.pt
    • Conf Proc IEEE Eng Med Biol Soc. 2010 Jan 1;2010:4602-5.

    AbstractA recursive system identification algorithm that merges PK/PD information in a minimally parameterized Wiener model for the NMB level is presented. The results show that the coupling between one parameter from the linear block and one from the static nonlinearity is advantageous, when evaluated on a database of 60 real collected NMB cases.

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