• Cristiane Rickli, Danielle Cristyane Kalva, Gustavo Henrique Frigieri, Adriana Fatima Menegat Schuinski, Sérgio Mascarenhas, and José Carlos Rebuglio Vellosa.
• PhD. Professor, Centro Universitário Integrado, Campo Mourão (PR), Brazil.
• Sao Paulo Med J. 2022 May 1; 140 (3): 398405398-405.

BackgroundThe high number of patients with end-stage kidney disease (ESRD) on hemodialysis makes it necessary to conduct studies aimed at improving their quality of life.ObjectivesTo evaluate brain compliance, using the Brain4care method for intracranial pressure (ICP) monitoring, among patients with ESRD before and at the end of the hemodialysis session, and to correlate ICP with the dialysis quality index (Kt/V).Design And SettingCross-sectional study conducted at a renal replacement therapy center in Brazil.MethodsSixty volunteers who were undergoing hemodialysis three times a week were included in this study. Brain compliance was assessed before and after hemodialysis using the noninvasive Brain4care method and intracranial pressure wave morphology was analyzed.ResultsAmong these 60 ESRD volunteers, 17 (28%) presented altered brain compliance before hemodialysis. After hemodialysis, 12 (20%) exhibited normalization of brain compliance. Moreover, 10 (83%) of the 12 patients whose post-dialysis brain compliance became normalized were seen to present good-quality dialysis, as confirmed by Kt/V > 1.2.ConclusionsIt can be suggested that changes to cerebral compliance in individuals with ESRD occur frequently and that a good-quality hemodialysis session (Kt/V > 1.2) may be effective for normalizing the patient's cerebral compliance.

8 keywords...

hide…