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- Mitsumasa Okano, Katsuhiko Yoneda, Yoshihide Ichise, Sentaro Kusuhara, Naokazu Muramae, Kenta Mori, Kazunori Otsui, and Kazuhiko Sakaguchi.
- Division of General Internal Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.
- Intern. Med. 2023 Jul 1; 62 (13): 200920122009-2012.
AbstractA 38-year-old man with deep vein thrombosis associated with Behçet's disease (BD) was admitted to our hospital due to worsening symptoms despite the initiation of direct oral anticoagulants (DOACs). Administration of oral prednisolone and an intravenous anti-tumor necrosis factor-alpha (TNF-α) monoclonal antibody dramatically improved his symptoms. In addition, he was incidentally diagnosed with autosomal dominant polycystic kidney disease, which increases the risk of aortic aneurysms. BD also increases the risk of aortic aneurysms. This case suggests that immunosuppressive treatment is effective in patients with inflammation-related DOAC-refractory venous thrombosis who also suffer from BD.
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