• Niger J Clin Pract · Nov 2022

    Case Reports

    Fatal cryptococcal meningitis in the Non-HIV infected: A case report.

    • I I Osaigbovo, S Igetei, and O J Omiunu.
    • Department of Medical Microbiology, University of Benin Teaching Hospital; Department of Medical Microbiology, School of Medicine, University of Benin, Benin City, Nigeria.
    • Niger J Clin Pract. 2022 Nov 1; 25 (11): 193119351931-1935.

    AbstractCryptococcal meningitis (CM) is underreported in the immunocompetent, the disease being more commonly associated with advanced human immunodeficiency virus (HIV) disease. We report the diagnosis, management, and eventual fatal outcome of CM in a non-HIV-infected man. Late presentation, delayed diagnosis, difficulties in accessing medications, and raised intracranial pressure (ICP) were contributory to his demise. Detailed history, a high index of suspicion, and laboratory workup coupled with prompt antifungal therapy and aggressive ICP management are essential for better outcomes.

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