• Tej D Azad, Sumil K Nair, Anita L Kalluri, Joshua Materi, A Karim Ahmed, Jawad Khalifeh, Nancy Abu-Bonsrah, Lisa N Sharwood, Robert C Sterner, Nathaniel P Brooks, Safwan Alomari, Farah N Musharbash, Kevin Mo, Daniel Lubelski, Timothy F Witham, Nicholas Theodore, and Ali Bydon.
• Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.
• World Neurosurg. 2023 Jan 1; 169: e121e130e121-e130.

BackgroundPrompt surgical decompression after traumatic spinal cord injury (TSCI) may be associated with improved sensorimotor outcomes. Delays in presentation may prevent timely decompression after TSCI.ObjectiveTo systematically review existing studies investigating delays in presentation after TSCI in low- and middle-income countries (LMICs) and high-income countries (HICs).MethodsA systematic review was conducted and studies featuring quantitative or qualitative data on prehospital delays in TSCI presentation were included. Studies lacking quantitative or qualitative data on prehospital delays in TSCI presentation, case reports or series with <5 patients, review articles, or animal studies were excluded from our analysis.ResultsAfter exclusion criteria were applied, 24 studies were retained, most of which were retrospective. Eleven studies were from LMICs and 13 were from HICs. Patients with TSCI in LMICs were younger than those in HICs, and most patients were male in both groups. A greater proportion of patients with TSCI in studies from LMICs presented >24 hours after injury (HIC average proportion, 12.0%; LMIC average proportion, 49.9%; P = 0.01). Financial barriers, lack of patient awareness and education, and prehospital transportation barriers were more often cited as reasons for delays in LMICs than in HICs, with prehospital transportation barriers cited as a reason for delay by every LMIC study included in this review.ConclusionsDisparities in prehospital infrastructure between HICs and LMICs subject more patients in LMICs to increased delays in presentation to care.Copyright © 2022. Published by Elsevier Inc.

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