• Am J Emerg Med · Nov 2022

    Heart failure alters diagnostic yield for pulmonary embolism in patients undergoing computed tomography pulmonary angiogram.

    • Jakrin Kewcharoen, Paresh Giri, M Reza Amini, Laren Tan, Dafne Moretta, Emily Barrett, E Lea Walters, and Dmitry Abramov.
    • Department of Medicine, Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, USA.
    • Am J Emerg Med. 2022 Nov 11; 64: 8118-11.

    IntroductionThere is limited evidence regarding the effects of a pre-existing heart failure (HF) on the diagnostic yield of pulmonary embolism (PE) evaluation in the Emergency Department (ED).MethodsElectronic medical record of consecutive adults who underwent a computed tomography pulmonary angiogram (CTPA) in the ED at Loma Linda University Medical Center between June 1, 2019 and March 25, 2022 were reviewed. Repeat studies for the same patient and patients with unspecified HF diagnoses or isolated right ventricular HF were excluded. Key demographics, lab values and vital signs, relevant medications were collected. Primary outcome was the incidence of PE on CTPA compared between patients with and without pre-existing HF.ResultsA total of 2846 patients were included in the study (602 patients with HF and 2244 without). In total cohort, 11.7% (n = 334) of patients had PE found on CTPA. The incidence of PE on CTPA was lower among patients with a history of HF than patients without a history of HF (12.5% vs 9%). A history of pre-existing HF was associated with a lower odds ratio for a positive PE study (OR 0.13, 95%CI: 0.03-0.57) in multivariable analyses.ConclusionsIn this study, we observed that the incidence of PE among patients who undergo CTPA was lower among patients with pre-existing HF compared to those without. Further studies should determine if HF is an important mitigating factor when risk stratifying patients for PE.Copyright © 2022 Elsevier Inc. All rights reserved.

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