• Internal medicine · Dec 2022

    Two Distinct Cases of Adult-onset Kawasaki Disease.

    • Takehiko Onoki, Takaya Metoki, Shinya Iwasawa, Kengo Kawano, Masato Kimura, Shigeo Kure, and Chiharu Ota.
    • Department of Pediatrics, Tohoku University Hospital, Japan.
    • Intern. Med. 2022 Dec 1; 61 (23): 352535293525-3529.

    AbstractKawasaki disease (KD) is a systemic vasculitis syndrome that mostly affects children under 4 years old. Among the reported KD cases, only 1% were over 10 years old. We herein report 2 cases of adult-onset KD (AKD) in 19- and 17-year-old boys diagnosed with a persistent fever and cervical lymphadenitis. Both patients showed cardiac complications, such as coronary artery dilation and myocarditis. Repeated intravenous immunoglobulin therapy was effective in the 19-year-old, while plasma exchange therapy was needed for the 17-year-old, with no sequelae noted at discharge. KD should be considered as a differential diagnosis for persistent fever in adults.

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