• V N Karetnikova, V V Kalaeva, M V Evseeva, O V Gruzdeva, M V Zykov, V V Kashtalap, and O L Barbarash.
• Research Institute for Complex Issues of Cardiovascular Diseases.
• Terapevt Arkh. 2019 Jun 15; 91 (6): 737973-79.

AimTo study polyvascular disease in patients with myocardial infarction (MI) and chronic kidney disease (CKD).Materials And MethodsA total of 954 patients older than 18 years old with ST-segment elevation MI (STEMI) up to 24 hours of pain onset were included in the study. Clinical and demographic data were collected for all patients, including physical examination, 16-lead electrocardiogram recording, echocardiography, laboratory assessment with the measurements of cardiospecific enzymes and serum creatinine. Glomerular filtration rate (GFR) was estimated according to the CKD-EPI equation. Of them, 771 (81%) underwent coronary angiography, duplex scanning of the brachiocephalic (BCA) and lower extremity arteries (LEA). Patients with stage 1-4 CKD diagnosed according to the criteria provided by the Russian Society of Nephrologists were allocated into a separate group (n=281; 36.5%). CKD stages were determined with the level of GFR. Patients with stage 5 CKD were excluded from the study. Renal dysfunction was defined as the presence of an estimated GFR less than 60 ml/min/1.73 m2.Results And DiscussionThe results of the study indicate a high prevalence of PolyVD in patients with CKD. Every second patient had LEA stenosis (p.

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