• Transplant. Proc. · Jan 2014

    A more than 20% increase in deceased-donor organ procurement and transplantation activity after the use of donation after circulatory death.

    • H Le Dinh, J Monard, M-H Delbouille, M-F Hans, L Weekers, C Bonvoisin, J Joris, S Lauwick, A Kaba, D Ledoux, A de Roover, P Honoré, J-P Squifflet, M Meurisse, and O Detry.
    • Department of Abdominal Surgery and Transplantation, University Hospital of Liege, Liège, Wallonia, Belgium.
    • Transplant. Proc. 2014 Jan 1;46(1):9-13.

    BackgroundOrgan procurement and transplant activity from controlled donation after circulatory death (DCD) was evaluated over an 11-year period to determine whether this program influenced the transplant and donation after brain death (DBD) activities.Material And MethodsDeceased donor (DD) procurement and transplant data were prospectively collected in a local database for retrospective review.ResultsThere was an increasing trend in the potential and actual DCD numbers over time. DCD accounted for 21.9% of the DD pool over 11 years, representing 23.7% and 24.2% of the DD kidney and liver pool, respectively. The DBD retrieval and transplant activity increased during the same time period. Mean conversion rate turning potential into effective DCD donors was 47.3%. Mean DCD donor age was 54.6 years (range, 3-83). Donors ≥60 years old made up 44.1% of the DCD pool. Among referred donors, reasons for nondonation were medical contraindications (33.7%) and family refusals (19%). Mean organ yield per DCD donor was 2.3 organs. Mean total procurement warm ischemia time was 19.5 minutes (range, 6-39). In 2012, 17 DCD and 37 DBD procurements were performed in the Liege region, which has slightly >1 million inhabitants.ConclusionsThis DCD program implementation enlarged the DD pool and did not compromise the development of DBD programs. The potential DCD pool might be underused and seems to be a valuable organ donor source.Copyright © 2014 Elsevier Inc. All rights reserved.

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