-
- John R White.
- Department of Pharmacotherapy, Washington State University, Health Sciences Building, Suite 210, PO Box 1459, Spokane, WA 99210, USA. Electronic address: whitej@wsu.edu.
- Med. Clin. North Am. 2015 Jan 1; 99 (1): 131143131-43.
AbstractSGLT2 inhibition offers a novel mechanism to mitigate hyperglycemia in patients with diabetes and the introduction of SGLT2 has added a significant new tool to the antihyperglycemic armamentarium. At present, 2 agents are approved for use in the United States and several more are in development. SGLT2 inhibitors are generally associated with a reduction in A1C of between 0.5% and 1%. SGLT2 inhibitors are associated with an increased incidence of urinary tract and genital infections but these infections are typically mild, responsive to treatment, and are not use limiting.Copyright © 2015 Elsevier Inc. All rights reserved.
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