• Internal medicine · Sep 2023

    Case Reports

    A Case of Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops.

    • Ryo Eto, Hiroaki Kawano, Ayaka Suzuki, Ryohei Akashi, Satoshi Ikeda, and Koji Maemura.
    • Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
    • Intern. Med. 2023 Sep 1; 62 (17): 251325162513-2516.

    AbstractVasospastic angina (VSA) can be worsened by oral nonselective beta-blockers. Ophthalmic carteolol eye drops are nonselective beta-blockers and effective against glaucoma and ocular hypertension. Systemic effects of ophthalmic beta-blockers on VSA have not yet been reported. We herein report a case of VSA that developed after a patient started carteolol eye drops for ocular hypertension. Even though benidipine, a calcium channel blocker, was started, a VSA attack with incessant non-sustained ventricular tachycardia occurred. Once the carteolol eyedrops were discontinued, the VSA resolved. This case demonstrates that carteolol eye drops can induce life-threatening VSA.

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