• Revista médica de Chile · Jan 2015

    Review Case Reports

    [Pneumomediastinum and cutaneous necrosis in dermatomyositis: Report of one case].

    • Natalia Gallardo C, Omar Valenzuela L, and Sebastián Ibáñez V.
    • Rev Med Chil. 2015 Jan 1; 143 (1): 120123120-3.

    AbstractWe report a 37 years old male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2,600 cells/mm³. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis.

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