• Tamara Leiva, Karen Basfi-Fer, Pamela Rojas, Fernando Carrasco, and Manuel Ruz O.
• Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, kbasfifer@med.uchile.cl.
• Rev Med Chil. 2016 Oct 1; 144 (10): 124712531247-1253.

BackgroundIncreasing meal frequency is commonly used in the clinical practice as part of the nutritional treatment of patients with type 2 Diabetes Mellitus (DM2), although its effect on metabolic control parameters is controversial.AimTo evaluate the association of energy intake, meal frequency, and amount of carbohydrates with fasting plasma glucose and glycosylated hemoglobin in a group of patients with DM2 without insulin therapy.Material And MethodsDietary intake was evaluated in 60 subjects with DM2 through three-day food records. The meal frequency was estimated establishing the main meal times considering snacks.ResultsMeal frequency was 4.7 ± 1.1 times per day. There was a positive association between glycosylated and fasting blood glucose levels (p <0.01). Meal frequency was associated with energy intake (p <0.01). When meal frequency, available carbohydrates and energy intake, body mass index and fasting plasma glucose were analyzed in a multiple linear regression model, fasting blood glucose was the variable that best predicted changes in glycosylated hemoglobin (45.5%). Meal frequency had no association with glycosylated hemoglobin.ConclusionsMeal frequency showed no association with metabolic control parameters in DM2 patients.

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