• Internal medicine · May 1992

    Case Reports

    Hemoglobin Andrew-Minneapolis (beta 144 (HCl) lysine----asparagine) in a Japanese family.

    • T Gomi, T Ikeda, and T Harano.
    • Department of Nephrology, Kanto-Teishin Hospital, Tokyo, Japan.
    • Intern. Med. 1992 May 1; 31 (5): 659661659-61.

    AbstractHemoglobin Andrew-Minneapolis, an abnormal hemoglobin with an asparagine residue substituted for a lysine at position 144 of the beta-globulin chains, was identified in three members of two generations in a Japanese family. The carriers of hemoglobin Andrew-Minneapolis showed false high levels of hemoglobin A1c, as measured by the standard cation exchange high performance liquid chromatography, and a moderate tendency for erythrocytosis. This family is the first report of this abnormal hemoglobin in Japan.

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