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- Y Maezawa, M Yamauchi, T Nakabayashi, K Toshima, K Ikeda, and G Toda.
- First Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
- Intern. Med. 1993 Feb 1; 32 (2): 128132128-32.
AbstractA 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 mumol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [beta 120 (GH3) Lys-->Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin.
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