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Internal medicine journal · Mar 2012
Case ReportsEfficacy of rituximab in refractory antisynthetase syndrome.
- V Limaye, P Hissaria, C-L Liew, and B Koszyka.
- Rheumatology Department, Royal Adelaide Hospital, South Australia, Australia. vidya.limaye@health.sa.gov.au
- Intern Med J. 2012 Mar 1; 42 (3): e4e7e4-7.
AbstractWe report the successful use of repeated administration of rituximab in a patient with antisynthetase syndrome refractory to conventional immunosuppressive medications. A literature review revealed that previous experience with rituximab in this condition has been sparse. The rationale for the use of B-cell depleting therapies in antisynthetase syndrome has been explored in light of the current understanding of the pathogenesis of this condition.© 2012 The Authors. Internal Medicine Journal © 2012 Royal Australasian College of Physicians.
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