• Am J Prev Med · May 2009

    Randomized Controlled Trial

    Influenza vaccination concerns among older blacks: a randomized controlled trial.

    • Ricardo J Wray, Trent D Buskirk, Keri Jupka, Christy Lapka, Heather Jacobsen, Ratna Pakpahan, Edith Gary, and Pascale Wortley.
    • Department of Community Health, Saint Louis University School of Public Health, St. Louis, Missouri 63104, USA. wray@slu.edu
    • Am J Prev Med. 2009 May 1; 36 (5): 429434.e6429-434.e6.

    ContextVaccination can decrease the morbidity and mortality caused by influenza, yet vaccination rates remain low, especially among minority groups. Previous studies have found that important barriers to vaccination include the fear of adverse reactions and concern that the vaccine causes influenza.BackgroundThis research aimed to assess the effects of messages designed to address concerns about the safety and effectiveness of vaccination among blacks aged >or=50 years.DesignIn a randomized controlled trial conducted in 2007 with pre-exposure and post-exposure measurements, participants were randomly assigned to read either the vaccine safety messages (VSM) developed for the study (treatment condition) or the vaccine information statement (VIS) currently given to those getting the vaccine (control condition).Setting/ParticipantsA total of 108 participants participated in the study. Data were collected in either participants' residences, community settings, or university conference rooms.Main Outcome MeasuresInfluenza vaccine-related beliefs and intention to receive vaccination were assessed.ResultsData analysis in 2007 and 2008 found that the randomization hypotheses of equal groups were retained. Participants exposed to the VSM showed greater improvement in post-exposure beliefs about how the vaccine works (p=0.0006) and the transmission of the flu (p=0.0034) as well as greater post-exposure disagreement with the belief that the vaccine causes influenza (p=0.0411).ConclusionsThe VSM affected beliefs about vaccine safety and effectiveness to a greater degree than did the VIS. These findings show that VSM are effective in changing beliefs empirically linked with influenza vaccination and vaccination disparities. The dissemination of VSM to older blacks may increase vaccination rates and reduce vaccination disparities.

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