• Tianzhu Wang, John H Zhang, and Xinyue Qin.
• Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
• Acta Neurochir. Suppl. 2011 Jan 1;110(Pt 1):219-23.

ObjectiveThe prognosis of patients with high-clinical-score subarachnoid hemorrhage remains poor, with early high mortality rate. Therefore, to predict the early outcome of patients after subarachnoid hemorrhage, several clinical factors were hypothesized to be related to death during hospitalization.MethodsEighty-nine cases after subarachnoid hemorrhage, divided into two groups (① death group; ② survival group) according to their clinical situations during hospitalization, were studied. Twelve factors, including gender, hypertension, intracranial aneurysm, cerebral vascular spasm, hydrocephalus and conscious disturbance during hospitalization, smoking, age, WFNS (World Federation of Neurological Surgeons) scale, Fisher grade, white blood cell count and blood glucose level at admission, were analyzed by using Chi-square test, t test, and Logistic multiple regression analysis.ResultsThe results of single-factor analysis indicated that ruptured intracranial aneurysm, conscious disturbance, increasing age, high WFNS scale, high Fisher grade, increasing white blood cell count and blood glucose level were statistically significant different between the two groups.The logistic analysis results showed that ruptured intracranial aneurysm (odds ratio [OR], 9.253; 95% confidence interval [CI], 0.617-98.263), high WFNS score (OR, 2.105; 95% CI, 1.275-5.204) and increasing white blood cell count (OR, 1.397; 95% CI 1.062-2.013) were the independent risk factors associated with death during hospitalization for patients with subarachnoid hemorrhage.ConclusionsIncreased white blood cell count may indicate poor outcomes for patients during hospitalization, even early death.

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