• Masui · Nov 2012

    Case Reports

    [Two cases of anaphylactoid reaction after administration of sugammadex].

    • Naohiro Ohshita, Yasuo M Tsutsumi, Asuka Kasai, Tomohiro Soga, Tomomi Kanamura, Toshiko Katayama, Akio Iseki, Yoshinobu Tomiyama, and Katsuya Tanaka.
    • Department of Anesthesiology, Tokushima University Hospital, Tokushima 770-8503.
    • Masui. 2012 Nov 1;61(11):1261-4.

    AbstractAnaphylaxis during anesthesia is a rare but life-threatening event. Sugammadex is a recently introduced drug that was specifically designed for the reversal of rocuroium and vecuronium-induced neuromuscular block. We describe the cases of a 74-year-old man and a 29-year-old man who developed an anaphylactoid reaction to sugammadex, presenting with cardiovascular collapse. Initial management consisted of fluid administration and intermittent i.v. ephedrine, epinephrine, and hydrocortisone. The patients made uncomplicated recovery and were discharged.

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