• Medicine · Jan 2018

    Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer.

    • Xiang-Ru Chen, Jia-Nan Dong, Fan Zhang, and Tian-Ling Yao.
    • Department of Ultrasound, The Second Affiliated Hospital of Mudanjiang Medical University Department of Rehabilitation Comprehensive Laboratory School of Image, Mudanjiang Medical University.
    • Medicine (Baltimore). 2018 Jan 1; 97 (1): e9243e9243.

    AbstractThis study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population.A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study.Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study.This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.

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