In 132 insulin-dependent diabetics (type I), between 15 and 45 years old (73 women and 59 men) glycosylated hemoglobin (HbA1), total cholesterol (TC), HDL-cholesterol (HDL-C) and total triglycerides (TG) have been determined. We observed that sex did not significantly influence the parameters studied. In the younger group of patients (aged between 15 and 30 years) HbA1, TC, TG were significantly greater than in the older group of patients (p less than 0.05 and p less than 0.01, respectively). ⋯ This was also found, although to a lesser extent, when considering TC levels (r = 0.45, p less than 0.05). However, no correlation between HbA1 and HDL-C was found in the total sample or regarding age. These results allow us to point out the usefulness and the application of HbA1 determination in evaluating the relationship between carbohydrate and lipid metabolism in type 1 diabetics.
E J Ezcurra Ferrer, M Licea Puig, and A Reyes Durán.
Rev Clin Esp. 1989 Mar 1; 184 (4): 182184182-4.
AbstractIn 132 insulin-dependent diabetics (type I), between 15 and 45 years old (73 women and 59 men) glycosylated hemoglobin (HbA1), total cholesterol (TC), HDL-cholesterol (HDL-C) and total triglycerides (TG) have been determined. We observed that sex did not significantly influence the parameters studied. In the younger group of patients (aged between 15 and 30 years) HbA1, TC, TG were significantly greater than in the older group of patients (p less than 0.05 and p less than 0.01, respectively). In this series, an elevated correlation among HbA1 and TG levels was found. This was also found, although to a lesser extent, when considering TC levels (r = 0.45, p less than 0.05). However, no correlation between HbA1 and HDL-C was found in the total sample or regarding age. These results allow us to point out the usefulness and the application of HbA1 determination in evaluating the relationship between carbohydrate and lipid metabolism in type 1 diabetics.