• Mei-Jung Chen, Shiau-Shian Huang, Kai-Dih Juang, and Chin-Hong Chan.
• From the Department of Psychiatry, Taichung Veterans General Hospital (M-JC, K-DJ, C-HC); Master of Psychology, Kaohsiung Medical University (M-JC); Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital (S-SH); School of Medicine, Chung Shan Medical University (S-SH); Faculty of Medicine, National Yang Ming University (S-SH, K-DJ); Candidate of Master of Epidemics, National Taiwan University, Taiwan, ROC (S-SH); Master of Arts, University of Chicago, Illinois, USA (K-DJ); National Defense Medical Center, Taiwan, ROC (C-HC); Master of Administrative Medicine, University of Wisconsin, Wisconsin, USA (C-HC).
• Medicine (Baltimore). 2015 May 1; 94 (17): e769e769.

AbstractAlthough catatonia is a well defined syndrome, the treatment of chronic catatonia remains an unresolved issue. Here, we report a successful treatment of a 30-year-old patient with treatment-resistant catatonic schizophrenia in 10 years by augmentation of selective serotonin reuptake inhibitors (SSRIs).We present a 30-year-old man with treatment-resistant catatonic schizophrenia who failed to respond to the treatment of benzodiazepines and antipsychotics for 10 years. He markedly improved after taking SSRIs. Now, he does not hold odd postures and begins to talk and show more facial expressions.We postulate that the therapeutic effect is related to the enhancement of 5-HT neurotransmission. SSRIs can be a considerable choice to treat chronic catatonia.

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