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- Chiaki Kamiya, Keiichi Odagiri, Naoki Inui, Takafumi Suda, and Hiroshi Watanabe.
- Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Japan.
- Intern. Med. 2023 Aug 1; 62 (15): 223122362231-2236.
AbstractPulmonary hypertension (PH) often complicates chronic lung disease. However, there are few reports of PH associated with diffuse panbronchiolitis, and there is no effective treatment. We herein report a 64-year-old woman diagnosed with PH due to diffuse panbronchiolitis. She received erythromycin, carbocysteine, and home oxygen therapy (1 L O2/min). After 4 months of therapy, the respiratory function (diffusing capacity of the lungs for carbon monoxide: 23.3% to 76.1%) and PH (mean pulmonary arterial pressure: 50 to 28 mmHg; pulmonary vascular resistance: 680 to 518 dynes・sec・cm-5; pre- vs post-therapy, respectively) had improved markedly.
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