• Rev Invest Clin · Jan 2022

    Review

    The Microbiota-Gut-Brain Axis: Clinical Applications in Obesity and Type 2 Diabetes.

    • Brandy Moser, Megan A Milligan, and Maria C Dao.
    • Dao Research Lab, University of New Hampshire, Durham, New Hampshire, United States.
    • Rev Invest Clin. 2022 Jan 1; 74 (6): 302313302-313.

    AbstractRecent investigations highlight the importance of the gut microbiota and bacteria-derived metabolites as key components in obesity and metabolic health. The microbiota-gut-brain axis presents promising targets for future obesity treatments and prevention. However, the current state of evidence and existing clinical applications of the microbiota-gut-brain axis have yet to be summarized in a thorough review. Therefore, we sought to examine current evidence on the effect of lifestyle, dietary, pharmacological, and surgical interventions on the microbiota-gut-brain axis. In addition, this review highlights potential next steps in research toward characterizing the role of the microbiota-gut-brain axis in metabolic health, along with possible interventions to address obesity.Copyright: © 2022 Permanyer.

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