• Alexandra L B Webb, Rene L Flagg, and Aaron S Fink.
• Department of Surgery, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA. Alexandra.Webb@med.va.gov
• Am. J. Surg. 2006 Nov 1;192(5):663-8.

BackgroundSurgical site infections (SSIs) result in significant postoperative morbidity and mortality. Although many of these infections can be prevented by timely administration of preoperative antibiotics, data suggest that many patients do not receive such therapy.MethodsA multidisciplinary team was convened that reviewed published guidelines, made antibiotic recommendations, and addressed administration issues. Responsibility for antibiotic administration was shifted from preoperative nursing staff to the anesthetist. Electronic quick orders were developed to encourage appropriate antibiotic selection and simplify order creation.ResultsTimely administration of preoperative antibiotics improved from 51% to 98% from February 2005 to February 2006. Appropriate antibiotic administered improved from 78% to 94%. The clean wound infection rate decreased from 2.7% to 1.4% over the same time period.ConclusionA multidisciplinary approach to prophylactic antibiotic use, including computer-guided decision support, facilitates appropriate preoperative antibiotic use, resulting in a significant decrease in surgical wound infections.

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