• J. Korean Med. Sci. · Dec 2022

    Correlation Between Third Dose of COVID-19 Vaccines and Regional Case Fatality Rates During the Omicron Wave in Korea.

    • Youngook Jang, In Joong Kim, Sung-Sil Moon, Sun Bean Kim, and Jacob Lee.
    • Center for Area Studies, Korea Institute for International Economic Policy, Sejong, Korea. yojang@kiep.go.kr.
    • J. Korean Med. Sci. 2022 Dec 26; 37 (50): e347e347.

    AbstractThis study seeks to find the correlation between case fatality rates (CFRs) and third-dose vaccination coverage in 244 counties (si/gun/gu) of South Korea during the omicron variant wave. Multivariate regression analyses report that the higher third-dose vaccination rates were correlated with lower regional CFRs, when controlling for age structure. If the third-dose vaccination rate of a county is higher by 10%, it would have a CFR lower by 0.05% (95% confidence interval, 0.03-0.08%). As the number of cumulative confirmed cases in South Korea was 16,353,495 as of April 20, 2022, a lower CFR by 0.03-0.08% is equivalent to 4,394-12,448 lives (8.6-24.4 per 100,000) spared. County-specific characteristics, such as age structure, intensive care unit availability, and the level of non-pharmaceutical interventions may also affect the extent of this correlation. The conclusion implicates the potential role of coronavirus disease 2019 vaccines in reducing the pressure on the regional healthcare capacity.© 2022 The Korean Academy of Medical Sciences.

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