• Miri Schamroth Pravda, Daniel Yehuda, Nili Schamroth Pravda, and Eilon Krashin.
• Department of Internal Medicine A, Meir Medical Center, Kfar Saba, Israel, Department of Intensive Care Unit, Wolfson Medical Center, Holon, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
• Isr Med Assoc J. 2022 Dec 1; 25 (12): 847850847-850.

BackgroundData regarding risk factors for superficial thrombophlebitis (STP) cases presenting to a hospital is limited.ObjectivesTo investigate and stratify clinical and laboratory risk factors for STP.MethodsWe conducted a retrospective case control study comparing patients presenting to the emergency department with STP and age- and gender-matched controls. We collected data on multiple risk factors and five blood indices.ResultsThe study comprised 151 patients and matched controls. Patients with STP were more likely to have varicose veins (43.7% vs. 5.3%, P < 0.001), recent immobilization (14.6% vs. 1.3%, P < 0.001), obesity (36.4% vs. 18.5%, P = 0.001), a history of venous thromboembolism (VTE) or STP (27.2% vs. 0.7%, P < 0.001), and inherited thrombophilia (9.3% vs. 1.3%, P = 0.002). Following multivariate analysis, all five risk factors remained significant, with a history of VTE or STP associated with the largest risk (odds ratio [OR] 35.7), followed by immobilization (OR 22.3), varicose veins (OR 12.1), inherited thrombophilia (OR 6.1), and obesity (OR 2.7). Mean platelet volume was higher (8.5 vs 7.9 fl, P = 0.003) in STP cases.ConclusionsA history of VTE or STP, immobilization, varicose veins, inherited thrombophilia, and obesity serve as independent clinical risk factors for STP presenting to hospital.

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